Microneedling

Microneedling effectively treats fine lines and wrinkles by stimulating the production of collagen and elastin, which are essential proteins for maintaining skin elasticity and firmness. During the procedure, tiny, controlled needle punctures create micro-injuries in the skin, prompting the body’s natural healing response. This leads to the formation of new collagen and elastin, ultimately reducing the appearance of fine lines and wrinkles and improving skin texture.

A study assessed the efficacy and safety of an automated microneedling device for facial skin rejuvenation. ^[1] Forty-eight participants underwent four microneedling sessions, and improvements in wrinkles, skin laxity, and texture were observed at Days 90 and 150 compared to baseline. These improvements were confirmed through skin topography analysis. The treatment was well-tolerated with minimal discomfort and side effects, making it a favorable option compared to more invasive technologies like laser ablation and radiofrequency for skin enhancement.

In a study involving eleven female participants with mild to moderate facial wrinkling, the combined use of topical growth factor treatment and home-based microneedling over three months demonstrated significant improvements in skin texture, wrinkles, redness, and brown spots. ^[2] Subjective patient-reported outcomes also indicated increased satisfaction with skin and facial appearance, including specific facial areas. Adverse effects related to the skin were minimally observed, with no serious complications reported.

In this study involving 35 subjects aged 44 to 65, microneedling treatments administered over the face and neck demonstrated notable improvements in skin parameters. ^[3] These included increased dermal and epidermal density, enhanced facial elasticity, and changes in skin architecture. Additionally, collagen and elastin production increased, indicating potential skin rejuvenation and the production of a new extracellular matrix.

Treatment Options

Microneedling effectively treats fine lines and wrinkles by stimulating the production of collagen and elastin.

Microneedling is an effective treatment for acne scars by stimulating the skin’s natural healing processes. During the procedure, tiny, controlled needle punctures create micro-injuries in the skin, prompting the production of collagen and elastin, which are essential for skin repair and regeneration. Over time, this enhanced collagen production helps to fill in and smoothen the appearance of acne scars, leading to improved skin texture and reduced scarring.

In a meta-analysis of twelve studies involving 414 participants, microneedling without radiofrequency was found to be more effective in achieving objective scar improvement compared to fractional radiofrequency microneedling. ^[4] The study did not report any cases of secondary scarring or infection related to microneedling but did find a significant preference for microneedling due to its lower risk of postinflammatory hyperpigmentation. Overall, the results suggest that microneedling, especially without radiofrequency, is a favorable choice for the treatment of acne scarring.

In a study involving 50 patients (70% female, 30% male) treated for post-acne scarring with four sessions of micro-needling over two months, significant improvements in scar grades were observed. ^[5] Grade 4 scars improved by two grades in 73% of cases, and Grade 3 scars showed similar improvement in 70% of cases, while all Grade 2 scars were downgraded to Grade 1 after treatment. Statistical analysis demonstrated a significant improvement in scar grading. The study concludes that micro-needling is an effective method for aesthetically improving post-acne scarring.

In a clinical study involving ten patients with atrophic (indented) acne scars, three months of skin microneedling treatment (six sessions at two-week intervals) led to noticeable clinical improvement in scar appearance. ^[6] Histological analysis (a type of microscope study) revealed a statistically significant increase in collagen types I, III, and VII, as well as newly synthesized collagen, while total elastin decreased significantly after treatment. The study concludes that multiple minimally invasive sessions of skin microneedling are an effective and relatively risk-free treatment for post-acne atrophic scars, stimulating repair processes with minimal patient recovery time.

Treatment Options

Microneedling can help reduce the appearance of acne scars by stimulating the skin’s natural healing processes.

Stretch marks, also known as striae, are a type of skin scarring that occurs when the skin stretches or shrinks rapidly. They often appear as parallel lines or streaks on the skin and can vary in color from pink or red to purple or silver. While they are generally harmless, they can affect a person’s self-esteem and body image, leading to feelings of self-consciousness or insecurity, especially if they are prominent or in visible areas of the body.

Microneedling is a cosmetic procedure that can help treat stretch marks by stimulating collagen production and improving the texture and appearance of the affected skin. During the procedure, tiny needles create micro-injuries in the skin, which triggers the body’s natural healing response. As the skin heals, it produces new collagen and elastin fibers, which can help reduce the appearance of stretch marks over time, making them appear less prominent and faded.

A study compared the effectiveness of microneedling and fractional CO2 laser therapy in treating striae distensae (stretch marks). ^[7] They treated similar striae on each side of 40 patients, with no significant differences in outcomes between the two treatments. Both microneedling and CO2 laser therapy significantly reduced the size of striae, improved patients’ satisfaction, and had similar improvements in the visual analog scale (VAS). Importantly, no significant adverse effects were observed.

A study compared the effectiveness of plasma jet and dermapen treatments for striae distensae in 30 patients. ^[8] The results showed no statistically significant difference in terms of width, score of erythema (redness), and skin texture between the two methods after treatment. However, plasma jet caused more pain, while dermapen resulted in higher instances of hyperpigmentation and erythema. The width of the striae significantly decreased after dermapen treatment. In conclusion, both treatments were effective and promising for striae distensae with minimal side effects.

A study evaluated the clinical results and side effects of microneedling in 25 individuals with striae distensae. ^[9] The participants received 1 to 3 consecutive monthly microneedling treatments, and all striae showed at least 50% improvement after an average of 1.8 treatments, with 28% of patients experiencing more than 75% improvement. The location of striae on different body areas did not significantly affect the treatment’s effectiveness. Side effects were limited to temporary redness, and there were no infections or discoloration observed.

Treatment Options

Microneedling can help treat stretch marks by stimulating collagen.

Enlarged pores are visibly larger and more prominent openings in the skin’s surface, typically found on the face, particularly in the areas with more oil glands like the nose, forehead, and cheeks. They can result from various factors, including genetics, excess oil production, aging, and sun damage. Enlarged pores can affect a person’s self-esteem and appearance, as they can make the skin texture appear rough and contribute to the development of acne and blackheads, leading to concerns about one’s overall skin complexion and confidence.

Microneedling is a cosmetic procedure that can help treat enlarged pores by stimulating collagen production in the skin. During the procedure, tiny needles create controlled micro-injuries on the skin’s surface, triggering the body’s natural healing response. This process promotes collagen and elastin production, which can lead to skin tightening and improved texture, ultimately reducing the appearance of enlarged pores and giving the skin a smoother, more refined appearance.

A study collected data from 75 patients with enlarged facial pores who underwent microneedle fractional radiofrequency (MFRF)) treatment from January 2019 to December 2020. ^[10] This treatment causes multiple, controlled micro-perforations at the target area to stimulate natural wound healing. The researchers analyzed the efficacy and complications of MFRF in different facial areas and found that the improvement rate increased with more treatment sessions. Overall, the study confirms the safety and effectiveness of MFRF in improving enlarged facial pores.

A study assessed the clinical efficacy of fractional radiofrequency microneedle (FRM) treatment in addressing acne scars and large facial pores. ^[11] Thirty patients were enrolled, and the treatment involved delivering bipolar radiofrequency energy through the FRM device. Results showed that more than 70% of patients experienced an improvement in the grade of acne scars and Investigator Global Assessment of large pores. Additionally, skin surface roughness, dermal density, and microscopic and composite images improved, although transepidermal water loss (TEWL) and sebum measurement remained unchanged. The study suggests that FRM treatment, possibly by promoting dermal matrix regeneration, may be effective in enhancing acne scars and facial pores.

A study assessed the efficacy and safety of combined microneedle and sublative fractional radiofrequency treatment for acne scars in Asian individuals. ^[12] Twenty subjects with moderate to severe acne scars underwent three consecutive treatments over 12 weeks. Physicians observed that all subjects experienced grade 2 or higher clinical improvement, with 20% achieving grade 4, 50% grade 3, and 30% grade 2 improvements in the appearance of scars as well as enlarged pores. The subjects’ self-assessments showed good agreement with physician assessments. The treatment had a manageable side effect profile, with post-therapy crusting lasting 5.2 days and erythema lasting 2.5 days.

Treatment Options

Microneedling can help reduce the appearance of enlarged pores by stimulating collagen production.

Microneedling can effectively treat uneven skin tone and texture by stimulating the skin’s natural healing response. During the procedure, tiny needles create controlled micro-injuries in the skin’s surface, prompting the production of collagen and elastin. This increased collagen production helps to even out skin tone by reducing the appearance of pigmentation issues like sunspots and acne scars, while also improving texture by minimizing the appearance of fine lines, wrinkles, and rough areas. Over time, microneedling can lead to smoother, more radiant skin with a more even tone and texture.

A trial examined the use of microneedling in combination with a novel human recombinant growth factor complex (PolyGF) for skin improvement. ^[13] Twenty female participants aged 35 to 60 received four microneedling treatments, either with or without PolyGF, and various skin parameters were assessed. The study found that the addition of PolyGF led to significant improvements in skin texture and hydration, as measured by both provider imaging and patient self-assessment, compared to the control group. While microneedling alone had positive effects on several skin parameters, the combination with the growth factor complex showed superior results in enhancing skin texture and moisture.

In a study involving 35 healthy adults seeking to reduce facial wrinkles, participants received four monthly microneedling procedures according to manufacturer instructions. ^[14] Wrinkle improvements were assessed by blinded raters comparing baseline and 90-day post-procedure images, and subjective assessments were also conducted. The results, based on 32 completed subjects with an average age of 56.3 years, showed significant wrinkle improvement, as well as high satisfaction rates with the treatment, suggesting that microneedling is a viable and minimally invasive option for facial wrinkle treatment.

A study assessed the effectiveness of microneedle mesotherapy in reducing skin discoloration using the gray-level co-occurrence matrix (GLCM) method, a tool used in skin discoloration analysis. ^[15] Twelve women aged 29 to 68 underwent four microneedle mesotherapy treatments with a solution containing 12% ascorbic acid on their forearm skin. Image analysis revealed an average 10.6% increase in skin brightness and a 10.7% decrease in GLCM contrast. Overall, the findings suggest that microneedle mesotherapy can effectively reduce skin discoloration.

Treatment Options

Microneedling can effectively treat uneven skin tone and texture by stimulating the skin’s natural healing response.

Skin laxity refers to the loss of elasticity and firmness in the skin, often associated with aging or rapid weight loss. It can affect a person by causing sagging and wrinkles, making them appear older than their actual age. Additionally, skin laxity can lead to self-esteem issues and a decreased sense of confidence, as individuals may be unhappy with their appearance due to the changes in their skin’s texture and tightness.

Microneedling can help treat skin laxity by stimulating collagen production in the skin. During the procedure, tiny needles create controlled micro-injuries in the skin, triggering the body’s natural healing process. This results in the production of new collagen and elastin fibers, which can improve skin elasticity, firmness, and overall texture, effectively reducing the appearance of skin laxity.

A case study explored the use of radiofrequency (RF) microneedling to improve skin laxity on a woman’s thighs following significant weight loss. ^[16] Two sessions of subcutaneous RF microneedling were conducted five months apart, resulting in a noticeable improvement in cellulite and skin laxity observed two months after the second treatment. The patient reported satisfaction with the results, suggesting that RF microneedling could be a non-surgical option for addressing skin laxity.

A study examined the safety and effectiveness of a temperature-controlled Micro-Fractional Radiofrequency (MFR) device for addressing facial fine lines and laxity. ^[17] Fifteen Korean participants, with a median age of 46, underwent a single MFR treatment session. The results showed immediate changes in collagen fibers and dermal shrinkage, with increased elastin and collagen observed at the 4-month follow-up. The majority (86.7%) of participants reported satisfaction with the results, and objective assessments by dermatologists also indicated significant improvements.

A study involved 31 female participants with cellulite, skin laxity, and subcutaneous fat excess in various body areas. ^[18] They received a single dermal and/or subcutaneous treatment, and assessments were made at 1, 3, and 6 months post-treatment. The results showed significant improvements in skin laxity, as assessed by investigators and subjects, particularly in the upper arms and bra-line areas. Treatments were generally well-tolerated, with mild side effects such as redness and swelling. The study concludes that microneedle fractional radiofrequency offers a promising single-treatment approach to enhance the appearance of body skin laxity and localized fat in specific regions.

Treatment Options

Microneedling can help treat skin laxity by stimulating collagen production in the skin.

Hyperpigmentation is a common skin condition characterized by the darkening of patches or areas of the skin. This darkening occurs due to an excess production of melanin, which is the pigment responsible for giving color to the skin, hair, and eyes. Hyperpigmentation can affect people of all skin types and colors and can occur on any part of the body.

Microneedling can help treat hyperpigmentation by stimulating the skin’s natural healing response. During the procedure, tiny needles create controlled micro-injuries in the skin, prompting the production of collagen and elastin. This process can improve the appearance of hyperpigmented areas by encouraging the turnover of damaged skin cells and promoting a more even distribution of melanin, leading to a reduction in pigmentation over time.

A study assessed the improvement of acne scar pigmentation in patients with dark skin using microneedling. ^[19] Secondary objectives included evaluating post-acne scarring improvement and the safety of microneedling in pigmented skin. A total of 39 patients with darker skin completed the study. Microneedling treatment resulted in statistically significant improvements in both scar and pigmentation scores, with minor and transient side effects.

In one study, 20 patients received microneedling on one side of their face and mesoneedling on the other side for four monthly sessions. ^[20] The effectiveness of the treatments was then assessed. Both microneedling and mesoneedling reduced the difference in pigmentation between melasma and normal skin, with statistically significant differences favoring microneedling.

A study compared the effectiveness and safety of combining skin microneedling with depigmenting cream versus using depigmenting cream alone for treating melasma. ^[21] Twenty patients received the combined treatment while 20 received only the depigmenting cream. The study found a significant reduction in the modified Melasma Area and Severity Index (MASI) score in the combined treatment group, indicating that the combination of microneedling and depigmenting cream yielded better results in melasma treatment compared to topical treatment alone.

Treatment Options

Microneedling can help address hyperpigmentation by encouraging the turnover of damaged skin cells and promoting a more even distribution of melanin.

Cellulite is a common cosmetic concern characterized by the appearance of dimpled or lumpy skin, often resembling an orange peel or cottage cheese. It typically occurs on the buttocks, thighs, hips, and abdomen, and is more common in women than men. While cellulite is not a medical condition and is generally harmless, it can affect a person’s self-esteem and body image, leading to self-consciousness and reduced confidence, especially in situations where the affected areas are visible, such as when wearing swimwear or shorts.

Microneedling can help improve the appearance of cellulite by stimulating collagen production and promoting skin tightening. During the procedure, tiny needles create controlled micro-injuries in the skin, triggering the body’s natural healing response. This results in increased collagen and elastin production, which can lead to firmer, smoother skin and a reduction in the dimpled appearance of cellulite over a series of treatments.

A study assessed the safety and efficacy of a subcutaneous microneedle RF treatment for posterolateral (the back and outer portion) thigh cellulite. ^[22] Fifty subjects with Nurnberger-Muller Grade II or III cellulite received one subcutaneous microneedle RF treatment, and the effectiveness was evaluated by dermatologists. The study demonstrated a procedural success rate of 93% at the 6-month follow-up, with no adverse events reported, indicating that this treatment is both safe and effective for long-term cellulite reduction in a single session.

In one study, a microneedle radiofrequency device previously shown to improve cellulite severity was used to enhance the aesthetic appearance of skin laxity and localized fat deposits in areas like the upper arms, bra-line, and suprapatellar region (above the kneecap). ^[23] Thirty-one female subjects with varying skin types received a single treatment, and assessments at 1, 3, and 6 months revealed improvements in global aesthetic improvement and skin laxity, both from investigator and subject perspectives. Treatment satisfaction was generally high and side effects such as transient redness, swelling, and mild bruising were reported but well-tolerated.

A study explored the anti-cellulite effects of Vitex agnus-castus and Tamarindus indica extracts using safe and effective polymeric microneedles (MNs) as a non-invasive delivery system. ^[24] The chosen plant extracts were assessed for their antioxidant properties and 3D-printing techniques were employed to create MNs suitable for skin penetration. The results showed that MNs loaded with these extracts had a positive impact on normalizing skin oxidative balance and reducing inflammation, suggesting a promising avenue for cellulite management.

Treatment Options

Microneedling can help improve the appearance of cellulite by stimulating collagen production and promoting skin tightening.

Microneedling can potentially help treat hair loss by stimulating hair follicles and promoting hair growth. During microneedling for hair loss, tiny needles create micro-injuries in the scalp, which triggers the body’s natural wound healing response and increases blood flow to the hair follicles. This process may lead to the release of growth factors and the activation of dormant hair follicles, ultimately resulting in improved hair thickness and density.

A study investigated the impact of microneedling with different penetration depths on hair growth in patients with androgenetic alopecia (AGA), a genetic and hormonal condition characterized by gradual hair thinning and loss. ^[25] Sixty patients with moderate to severe AGA were divided into three groups: a control group receiving minoxidil 5% lotion alone, group A receiving minoxidil 5% lotion and biweekly microneedling with a depth of 1.2 mm, and group B receiving minoxidil 5% lotion and biweekly microneedling with a depth of 0.6 mm over 12 weeks. Results showed that all groups experienced a significant increase in hair count and thickness compared to baseline, with group B (0.6 mm depth) demonstrating the most substantial improvements.

An online literature search yielded 22 clinical studies involving 1127 subjects evaluating the use of microneedling (MN) for hair loss disorders. ^[26] These studies showed that MN, used as an adjunct therapy, improved hair parameters in various types and severities of hair loss, employing different needling devices, depths (0.50–2.50 mm), and session frequencies. In subjects with alopecia areata (an autoimmune disease that attacks hair follicles and causes hair loss), MN showed improvement as a standalone therapy or when paired with various treatments. No serious adverse events were reported.

In another study, the efficacy and safety of a newly developed home-use microneedle device for treating pattern hair loss were investigated. ^[27] Twenty-nine patients were divided into three groups: those using the microneedle device alone, a combination of the microneedle device and 5% minoxidil solution, and those using 5% minoxidil solution only, with treatments administered twice a week for 6 months. Results showed that the combination group exhibited improvements in hair count and patient self-assessment scores. The study suggests that the home-use microneedle device, in combination with a minoxidil solution, may offer a safe modality for enhancing hair growth.

Treatment Options

Microneedling can improve hair thickness and density by stimulating hair follicles and promoting hair growth.

Most people experience only mild discomfort during the procedure. To minimize discomfort, a numbing cream is usually applied to the treatment area.

The number of sessions required varies depending on your specific concerns. Typically, a series of 3-6 sessions spaced a few weeks apart is recommended for optimal results.

The results of microneedling can last for several months to a year or more, but maintenance sessions may be needed to sustain the benefits.

Yes, microneedling can be combined with other cosmetic treatments, such as laser therapy or chemical peels, for enhanced results. Consult with your practitioner to determine the best approach for your needs.

After the treatment, you need to:

• Avoid strenuous exercise.
• Avoid saunas and hot tubs.
• Avoid sun exposure.
• Avoid using harsh skincare products.
• Avoid using makeup.
• Avoid touching your face.

Most people can resume their normal activities within a few days after microneedling. However, it may take up to two weeks for your skin to fully heal.

You should start to see results from microneedling within a few weeks. However, it may take several months to see the full benefits of the treatment.